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The 9 Best Probiotics For Women 50+ For Menopause Belly, Vaginal Health & More*
As you age, your microbiome ages with you. With each passing decade, we can lose microbial diversity1 thanks to factors like age-associated stressors and immune challenges. This makes high-quality probiotics even more valuable once you hit the back half of life. Certain bacterial strains can also help support women 50+ as they navigate the side effects of perimenopause, menopause, and postmenopause.*
Here's what women over 50 should look for in a probiotic supplement and nine of the best options available.
The best probiotics for women 50+
Should women over 50 take probiotics?
Probiotic supplements—which help augment the microbiome with an influx of good bacteria—can be helpful at any age. However, they may be particularly effective for managing some of the hormone-driven challenges of menopause.
For example, certain probiotic strains have been associated with increased production of follicle-stimulating hormone2 (FSH). FSH stimulates the production of estrogen, and it can be helpful for balancing temperature regulation, vaginal health, and mood during menopause.*
The decline in progesterone levels during menopause can negatively affect gastrointestinal tract functioning3 and contribute to gas, bloating, and weight gain—all issues that the right probiotics can help out with4 too.*
Some strains can also support a healthy vaginal microbiome and reduce the vaginal dryness5 associated with postmenopause, according to research.*
Other science-backed benefits of probiotics for women 50+ include improved bone strength and density6 and weight management/cardiometabolic health2.* One particularly interesting study out of Korea on 63 healthy women over 65 years old found that those who took a probiotic containing Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI for 12 weeks experienced less stress and more mental flexibility7 than those who took a placebo.*
We have roughly the same number of bacteria in our body as we do human cells8, so it pays to tend to these microbes with a probiotic that's targeted for your exact needs. The key is taking bacterial strains that have been clinically studied for the benefits you're after.
To help you on your search, mindbodygreen's vice president of scientific affairs Ashley Jordan Ferira, Ph.D., RDN, identified the best probiotics on the market for women 50+ right now.
Summary
How we picked
For women
These formulas boast good bugs (probiotics!) targeted for women's needs and wants, from supporting the vaginal microbiome and urogenital tract health to targeted strains for gut health and more.*
Probiotic specificity
Since each probiotic strain has unique characteristics and health benefits, we prefer and elevate products that share with genus, species, and strain info per probiotic, as well as CFU dose info per strain.
Quality testing
We elevate reputable brands that prioritize quality testing, to ensure the potency of the probiotic and prebiotic ingredients, while also placing an emphasis on purity (limiting heavy metals, microbials, etc.).
Sustainability
From ingredient sourcing to packaging decisions, we prefer products created with sustainability in mind. As such, we highlight key certifications, as well as recyclable and eco-friendly containers.
The best probiotics for women 50+
Best for gas and bloating: mindbodygreen probiotic+
Pros
- Helps aid digestion and ease bloat*
- Supports healthy weight*
- Contains 4 targeted, clinically studied strains for gut health
- Sustainable packaging
Cons
- Daily regimen to maximize benefits
Serving size:
1 capsule dailyStrains researched for::
Weight managementRegularityGut health & comfortCFU:
32 billionWomen are twice as likely as men to experience bloating and struggle with regularity, and hormonal changes after age 50 only make matters worse.
Enter: mindbodygreen's probiotic+ supplement, which contains four probiotic strains specifically studied for gut health and comfort. In this probiotic, you'll find clinically relevant amounts of B. lactis Bi-07 to ease bloating and promote comfort, B. lactis B420 to help with healthy weight management, B. lactis HN019 to support digestion and regularity (while reducing gas), and L. acidophilus NCFM to encourage healthy bowel movements. It's a one-stop shop for healthy, comfortable digestion. Many reviewers notice a real difference within a few weeks of taking the product. While probiotic+ has proven helpful for women over 50, it's suitable for younger women and men as well.*
Save money when you sign up for a mindbodygreen probiotic+ subscription ($69/month), or buy once for $80. New customers save 10% on their first order with promo code MBG10.
Best for weight management: Metagenics UltraFlora Control
Pros
- Contains clinically studied strain for weight management*
- Clean formula
Con
- Single-strain formula may be a con to some
Serving size:
1 capsule dailyStrains researched for::
Weight managementCFU:
10 billionMany women experience weight fluctuations as they age and during perimenopause/menopause. When paired with a healthy diet and exercise, the right probiotics can help support a healthy body weight.*
This single-strain probiotic from legacy brand Metagenics delivers 10 billion CFUs of Bifidobacterium lactis B420: a strain that supports a healthy weight through reductions in caloric intake, abdominal fat mass, and waist circumference. It's far and away the most rigorously studied strain for weight management.
Many reviewers have found that this supplement gets to work almost immediately, and it helps with other markers of gastrointestinal health (think: more regularity and less gas), too.*
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Best for vaginal health: Thorne Women's Daily Probiotic
Pros
- Affordable
- Contains strains studied for vaginal health*
Cons
- Plastic packaging
- Some strains are in a proprietary blend
Serving size:
1 capsule dailyStrains researched for::
Vaginal healthVaginal pHCFU:
10 billionMore than half of postmenopausal women experience occasional vaginal dryness. Research has shown that when compared with estrogen alone, estrogen combined with probiotics can significantly improve key vaginal health scores.
Lactobacillus is the bacterial genus that plays a protective role along the microbiome of the vaginal canal and urinary tract. This blend from Thorne includes eight strains of Lactobacillus bacteria—most notably L. acidophilus UALA-01, which has been shown to promote a balanced vaginal pH, and L. reuteri RC-14, which has been shown to help protect against urogenital tract concerns.
Though it does contain proprietary blends, which aren’t ideal from a transparency standpoint, Thorne's supplement contains thoughtful strains that are targeted for vaginal health.*
Best for women’s urinary tract health: MegaFood Women’s Probiotic + Prebiotic
Pros
- B Corp certified
- Added prebiotics
- Contains clinically studied strains for vaginal and urinary tract health*
Cons
- Needs to be taken with a meal
- Needs to be stored in the fridge or freezer
Serving size:
2 capsules daily, with foodStrains researched for::
Vaginal healthUrinary tract healthCFU:
50 billionHormonal changes can also cause changes in the lining of the vagina and urinary tract that make them more susceptible to immune challenges. Taking MegaFood Women’s Probiotic + Prebiotic can help re-invigorate the urinary tract with 14 healthy bacterial strains, most notably Lactobacillus rhamnosus HN001 and Lactobacillus plantarum LP115.
These have been shown in preclinical studies to help protect against urinary tract health concerns, and they might have a beneficial impact on mood too, as HN001 has been studied for combatting anxiousness and mood support during the postpartum period. The probiotic also contains prebiotics (from beet, burdock, and dandelion roots) to feed these beneficial bacteria, and the added cranberry for further protection against harmful bacteria is a nice touch.*
You can feel good buying from MegaFood, a certified B Corp for its commitment to sustainability. Just note that this product should be taken with a meal and stored in the fridge or freezer upon arrival.
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Best for regularity: Ora Organic Trust Your Gut Powder
Pros
- No added sugar
- Contains prebiotics
Cons
- Powder delivery not suitable for everyone
Serving size:
1 scoopStrains researched for::
RegularityGut health & comfortCFU:
20 billionIf you prefer a non-capsule option, this probiotic from Ora comes in a flavored powder that can be mixed with water or blended into smoothies, oatmeal, yogurt, etc. One scoop delivers seven bacterial strains in the Lactobacillus and Bifidobacterium genus that are geared toward digestive health, mood, and a healthy inflammatory response (though Ora recommends starting with half a scoop a day to get used to the product). As far as powders go, these are super clean and get their "apple raspberry" and "lavender lemonade" flavors from natural, organic sources with no added sugar.
This option may be particularly beneficial for those who struggle with regularity since its strains have been studied for both slowing things down and getting things moving. It also contains prebiotic fiber from organic Jerusalem artichokes for added gut support.*
Pros
- Added nutrients for menopausal health*
- Accompanying app for health tracking
Cons
- Contains dairy (milk)
Serving size:
2 capsules daily, with foodStrains researched for::
Weight managementGut health & comfortCFU:
25 billionThis product gets rave reviews for its ability to ease menopausal lifestyle challenges and help with temperature regulation, mental clarity, and mood. It contains probiotic strains that have been studied for weight management and a healthy inflammatory response, and it has a suite of botanicals geared toward menopausal women. Magnolia bark extract helps support sleep quality; red clover helps promote hormonal balance; and chaste berry extract offers mood support and reduces anxiousness. The accompanying MenoLife app also lets users keep track of how the non-hormonal supplement is working for them over time.*
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Best multivitamin with probiotics: Garden of Life Vitamin Code 50 and Wiser Women's Multi Capsules
Pros
- Contains added fruit and veggies blend
- Contains essential vitamins and minerals
Cons
- 4 capsules daily
- Low CFU count
Serving size:
4 capsules dailyStrains researched for::
Gut health & comfortCFU:
500 millionLooking for a probiotic that can also help meet your nutritional needs? This option from Garden of Life contains a modest amount of Lactobacillus bulgaricus and Lactobacillus plantarum for gut health, more than 20 powdered organically grown fruits and vegetables, and a well-rounded array of essential vitamins and minerals. It's essentially a multivitamin, a fruit and veggie powder, and a probiotic in one—hence why each serving is a hefty four capsules. Reviewers note that even though taking so many capsules can be a pain, the product helps them feel more energized, focused, and strong.*
Best probiotic for menopause belly: Designs for Health Probiotic Supreme
Pros
- Contains clinically studied strains for healthy body composition*
Cons
- Expensive
- Needs to be refrigerated
Serving size:
1 capsule dailyStrains researched for::
Weight managementUrinary tract healthCFU:
15 billionAnother fun side effect of menopause is the accumulation of body fat in the lower belly and torso, leading to what some call "menopause belly." This probiotic by Designs for Health can help give you a leg up on a healthy and comfortable midsection with strains that have been studied to lower fat mass (B. Breve B-3), and it also has strains for immunity (L. Acidophilus La-14) and urinary tract health (L. Casei Lc-11).*
It's designed as a slow-release formula to help ensure more of its beneficial probiotics actually reach the digestive tract. One capsule a day is all you need, but the product should be refrigerated to maintain quality.
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Pros
- Contains added prebiotics and cranberry
- No artificial flavors or synthetic colors
Cons
- Added sugars
- Low CFU count
Serving size:
2 gummiesCFU:
2 billionGot a sweet tooth? Probiotic gummies are here for you. This option from Renew Life packs in two strands, B. coagulans SNZ 1969 for digestive regularity and B. subtilis DE111, which has been studied for healthy cholesterol levels, plus prebiotics and cranberry powder for urinary health.*
It's a relatively healthy option as far as gummies go, with no artificial flavors or synthetic colors, though each serving does contain 3 grams of added sugar. At 2 billion CFUs per serving, it also doesn't deliver as many good bugs as many other picks on the list.
How to choose
When deciding on the right probiotic for you, you'll first want to consider your unique needs. Eager to ease bloat and gas? Look for a probiotic that uses strains specifically for gut health. Working on your weight management? There are strains that have been studied for that, too. Ideally, the company you're buying from will be transparent about the exact bacteria in its product (down to the strain) so you can know exactly what you're putting in your body and why.
As you're shopping, take note of the number of colony-forming units (CFUs) in each product. While more CFUs aren't necessarily better, you'll want to make sure each strain is present in a clinically relevant amount—i.e., one that's been shown to be beneficial in scientific testing. This can get confusing, so we broke down everything you need to know about probiotic dosing here.
Finally, you'll want to choose a probiotic that is easy to incorporate into your life. If you're not great about taking pills, a gummy option might be more suitable (just look out for added sugar). If you always forget to take supplements with meals, opt for a probiotic that can be consumed without food.
Pair your new probiotic with a gut-healthy diet and regular physical activity9 to protect your diverse microbiome as you age—and support longevity and health span in the process10.
Health benefits
These are just a few of the probiotic benefits that may be of special interest to women over 50:*
Frequently Asked Questions
Are probiotics safe for women over 50?
Probiotics are generally regarded as safe to take at any age, though you may experience gas or bloating when introducing new bacterial strains into your system. It's never a bad idea to check with your doctor before introducing a new supplement into your routine, though, especially if you have underlying health issues.
What is the best probiotic for women over 50?
It depends on what you're using it for! No two microbiomes are the same, so different people will find success with different supplements. But if you're looking for digestive support, mindbodygreen's probiotic+ supplement contains four strains clinically studied for gut health, and if it's urinary tract health you're after, MegaFood Women's Probiotic + Prebiotic has strains researched for this purpose.*
What's the best probiotic for women's vaginal health?
Thorne's Women's Daily Probiotic came out on top in our "best for vaginal health" category thanks to strains that have been shown to support vaginal health and pH balance.*
The takeaway.
It's never too late to introduce a high-quality probiotic into your routine and get the good bugs on your side. Probiotics can help women over 50 support their weight, digestive health, heart health, vaginal and urinary tract health, and more.* But they don't work in isolation. Be sure to pair them with other microbiome-supporting habits like eating a nutrient-dense diet, managing stress, and getting plenty of exercise.
Meet The Experts
16 Sources
- https://www.nature.com/articles/s41575-022-00605-x#
- https://pubmed.ncbi.nlm.nih.gov/34109594/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9150547/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900870/
- https://pubmed.ncbi.nlm.nih.gov/35464937/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929795/#
- https://pubmed.ncbi.nlm.nih.gov/32300799/
- https://pubmed.ncbi.nlm.nih.gov/26824647/
- https://pubmed.ncbi.nlm.nih.gov/31967716/
- https://pubmed.ncbi.nlm.nih.gov/33619379/
- https://www.sciencedirect.com/science/article/pii/S1756464619300684
- https://pubmed.ncbi.nlm.nih.gov/35967876/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176637/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953587/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967272/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219592/
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